Royal Air Force Typhoon FGR4s have conducted a mission with French warplanes in a combined operation against an underground arms cache in Syria operated by the Daesh militant organization, according to the UK's MoD.
The location, pinpointed through reconnaissance, was assessed as housing weapons and explosive materials, the statement said, and was situated in mountainous terrain just to the north of the ancient city of Palmyra in the heart of Syria.
"The RAF jets utilized Paveway IV guided bombs to strike a series of access tunnels providing entry to the site... early reports suggest the target was engaged successfully," officials stated.
There was no sign of any civilian casualties in the attack late on Saturday and each participating jet made a safe return, the defence officials confirmed.
The Typhoon FGR4s were backed up by a Voyager aerial refuelling aircraft.
Daesh - also known as Daesh - enforced jihadist rule over large swathes of Iraq and Syria prior to its 2019 collapse.
"This action shows the UK's leading role, and determination to work closely with allied nations, to eliminate any re-emergence of the terrorist group and their violent and radical beliefs in the Middle East," the British Defence Secretary John Healey said.
UK warplanes have conducted surveillance missions over Syrian airspace to "forestall any attempted resurgence" of IS subsequent to its military defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I want to thank all the members of British forces involved in this operation for their skill and their valour," Healey added. "Including them were thousands of British personnel stationed over the holidays. This mission, to eliminate militants who pose a risk to our way of life, shows how British military are always on standby, all year round, keeping Britain secure within its borders and strong abroad."
Last December, the American forces conducted what it called a "large-scale strike" on Daesh sites in the country, following an ambush claimed the lives of two US troops and a local interpreter in the Palmyra area.
The United Nations estimates IS still has roughly 5-7 thousand militants in both countries.